Ewing's Sarcoma Trial

vigilewingssarcomatrial.jpg

The purpose of this Phase 2 study is to compare VIGIL® engineered autologous tumor cell immunotherapy, with chemotherapy when given to patients with Ewing’s Sarcoma.  The Ewing's Sarcoma clinical trial is open at many centers in the United States and actively enrolling patients.                                                                                                    . 

Ovarian Cancer Trial

vigilovariancancertrial.jpg

The purpose of this Phase 2 study is to test if VIGIL® engineered autologous tumor cell immunotherapy, made from a patient's own ovarian cancer tumor cells, removed during surgery, prolongs recurrence-free survival when given in a maintenance setting.  The trial is open at many centers in the United States and actively enrolling patients.

PD-1/PD-L1 Combination Trials

vigilpd1combinationtrials.jpg

There are studies underway of Vigil® in combination with PD-1/PD-L1 inhibitors in non-small cell lung cancer, melanoma or skin cancer, and triple-negative breast cancer patients.  These pilot studies are designed to explore the combination of immune activating properties of Vigil® with checkpoint blockade by PD-1/PD-L1 inhibitors.

 

Participating in Clinical Trials

The NIH website states "Clinical trials are part of clinical research and at the heart of all medical advances. Clinical trials look at new ways to prevent, detect, or treat disease. Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments.

The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff. Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future."